Immunohistochemistry Kits and Reagents
Biotium NKX2.2(NX2/294), CF594 conjugate, 0.1mg/mL
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biolegend TotalSeqTM-Bn0196 anti-human C
TotalSeq™-Bn0196 anti-human CD235ab [HIR2]; Isotype: Mouse IgG2b, κ; Reactivity: Human; Apps: SB; Size: 10 μg
Biotium Tenascin(T2H5), CF594 conjugate, 0.1mg/mL
In Western blotting, this antibody reacts with two bands of ~MW of 210 kDa and 300 kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue
Biotium CD74(BU45), CF594 conjugate, 0.1mg/mL
Recognizes proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74. Its epitope is localized in the extracellular domain of CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has b
Medchemexpress LLC Enzalutamide Ready For Reconst | HY-70002-10MM 1ML IN DMSO
Enzalutamide Ready For Reconst
Abcam Mouse and Rabbit Specific HRP/DAB IHC Detection Kit - Micro-polymer, 60ML
Rabbit/mouse dual, HRP/DAB detection IHC kit is a colorimetric micro-polymer assay kit used to detect mouse and rabbit primary antibodies in immunohistochemistry (IHC). - Cited in over 65 publications - No need for endogenous biotin blocking - Includes ready-to-use blocking reagents - Higher sensitivity than streptavidin-biotin methods
The product is subject to the following: Abcam Restricted Use Statement
Leica Biosystems Bond Enzyme Pretreatment Kit
BOND ancillaries have been designed for Leica Biosystems fully-automated BOND systems: BOND-MAX and BOND-III systems. Used in the development and validation of BOND ready-to-use primary antibodies and ISH probes - choose Leica Biosystems reagents for the assurance of a quality result in your laboratory.BOND Enzyme Pretreatment Kit consists of an enzyme concentrate and an enzyme diluent, which require mixing. The enzyme is diluted before use in the BOND Open Containers supplied. The diluted enzyme solution is used for enzymatic digestion on the automated BOND system.
Biotium Desmin (Muscle Cell Marker)(D33), Biotin conjugate, 0.1mg/mL
Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain -helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. Primary antibodies are available purified, or with a selection of fluorescent CF
Biotium Complement C4d(C4D205), CF594 conjugate, 0.1mg/mL
This MAb is specific to Complement 4d (C4d) and it reacts with the secreted as well as cell-bound C4d.C4d is a degradation product of the activated complement factor C4b. Complement 4b is typically activated by binding of Abs to specific target molecules. Following activation and degradation of the C4 molecule, thio-ester groups are exposed, which allow transient, covalent binding of the degradation product Complement 4d to endothelial cell surfaces and extracellular matrix components of vascular basement membranes near the sites of C4 activation. The presence of C4d in peritubular capillaries is a key indicator for acute humoral (i.e. antibody-mediated) rejection of kidney, heart, pancreas and lung allografts. As an established marker of antibody-mediated acute renal allograft rejection and its proclivity for endothelium, this component can be detected in peritubular capillaries in chronic renal allograft rejection as well as hyperacute rejection, acute vascular rejection, a
Electron Microscopy Sciences IHC Retriever Section Block 125 ML
A new class of blocking solutions based on chemically modified and fragmented ultra-pure casein. Effectively reduces unwanted binding of primary antibody and conjugates you use to charged surface of the slide and tissue section. Greatly reduces non-specific binding while preserving the specific reaction, by saturating potential non-specific protein-protein interactions. Moreover, in contrast to BSA-based, IgGm casein or serum - based blocking solutions there is no interaction of specific antibody and blocking protein itself. or oth Is not comparable to other commercially available or home-made blocking solutions. Recommended for research and diagnostic pathology, especially for retrieved sections and polyclonal antibodies.
Biocare Medical, LLC Immunocare TBS Wash Buffer, 10X
Immunocare TBS Wash Buffer (sodium azide and thimerasol free) works well for manual and automated immunohistochemistry applications as well as other laboratory procedures requiring a high quality TBS buffer with superior pH stability. The buffer contains surfactant and allows for reagents to spread more uniformly across tissue sections on slides. It has been specifically formulated with Enzyme Activator for Alkaline Phosphatase detection systems. It can also be used on an automated staining system.
ABclonal Technology δ-Catenin/p120 Catenin Rabbit pAb
This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene.
Meso Scale Discovery RPLEX MSE Periostin/OSF2 ASYQP
The R-PLEX Mouse Periostin (OSF-2) Assay from Meso Scale Discovery is a multiplex immunoassay that measures periostin (OSF-2) in mouse samples such as serum plasma and cell culture supernatants This assay utilizes MSD s electrochemiluminescence (ECL) detection technology and provides high sensitivity a wide dynamic range and requires a low sample volume The assay can be fully automated and has a rapid 2 5 hour turnaround time It is available as a singleplex assay that measures only periostin or as a multiplex assay that measures periostin along with other analytes This assay allows the quantitative measurement of periostin which plays a role in cardiac remodeling and bone metabolism